Download CLC Genomics Workbench 10 Full Version + crack
CLC Genomics Workbench is a powerful solution developed by scientists for scientists to analyze and visualize next generation sequencing (NGS) data. Its cutting-edge technology incorporates unique features and algorithms that are widely used by scientific leaders in industry and academia to overcome bottleneck challenges associated with data analysis.
Resequencing
CLC Genomics Workbench supports the complete resequencing pipeline for detecting and comparing genetic variants. When dealing with high sample volumes efficient algorithms reduce run time while customizable analysis workflows and batch processing shorten hands-on time to a minimum.
CLC Genomics Workbench allows you to focus on the biological interpretation of detected variants.
Read mapping
The first step in resequencing is accurate read mapping. Our algorithm is optimized for high-quality mapping of large data volumes in a fast and memory-efficient way.
The algorithm offers comprehensive support for a variety of data formats, including both short and long reads, and all flavors of paired read data regardless of insert size or read orientation. It also supports the use of hybrid data sets. Local realignment can drastically reduce false positive detection rates for certain variant types. Our goal is to reduce your manual work and focus on deriving biological meaningful results from raw NGS reads.
Transcription factor ChIP-Seq
Recent improvements promise deeper insights into transcriptional regulation even in the absence of control sample. Transcription factor ChIP-seq exposes defined peak regions characteristic of transcription binding sites throughout the whole genome. All made accessible through our tried and trusted interactive graphical user interface.
Workflow
Workflows streamline selected tools into one analysis. Workflows can be run in batch making them a powerful tool for processing large numbers of samples with minimal user interventions. You can easily set up your own workflows and create and share workflow installer files with colleagues or other researchers following your scientific publications. Commercial add-ons introduce preconfigured example workflows to get you from data to publication faster.
RNA-Seq
The free “Advanced RNA-Seq plugin” integrates all the analysis steps – from secondary analysis of the reads to sophisticated statistics – into easy-to-use workflows, and gives access to a wide range of experimental designs, from case-control or multi-group experiments to multi-factorial experiments. All tools account for differences due to sequencing depth, removing the need to normalize input data. Multi-factorial statistics control for batch effects and support paired studies. Statistical results can be visualized in a genomic context as tracks, in a table view, or through the many visualization options leveraging metadata: volcano plots, 2D Heatmaps, Principal Component Analysis and Venn diagrams.
Histone ChIP-Seq plugin
Acetylation of histones is an important epigenetic adaptation associated with chromatin decondensation and up-, or down-regulated gene expression. The Histone ChIP-Seq plugin for CLC Genomics Workbench detects evidence for Histone acetylation marks in genes or other predefined genomic regions.
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